Lenvatinib 4 mg and 10 mg capsules are prescription medicines containing lenvatinib, a kinase inhibitor used in specific cancer treatment settings. The available strengths can be used as part of individualized dosing plans, including dose adjustments when required during treatment. Always review the current prescribing information before dispensing or using lenvatinib.
Lenvatinib 4 mg and 10 mg Capsules
Lenvatinib is supplied as hard capsules containing either 4 mg or 10 mg of lenvatinib. The medicine works by inhibiting several kinase pathways involved in tumor growth and blood-vessel formation, including VEGF receptors and other targets such as FGFR, RET, KIT, and PDGFRA.
Approved Uses and Treatment Settings
Depending on the applicable prescribing information, lenvatinib may be used for differentiated thyroid carcinoma, hepatocellular carcinoma, endometrial carcinoma in combination with pembrolizumab, and certain renal cell carcinoma treatment regimens. The indication, treatment combination, and recommended dose depend on the patient’s condition and the applicable regulatory labeling.
Lenvatinib Dosage Information
The recommended dose varies by indication. For example, the current U.S. prescribing information lists 24 mg once daily for differentiated thyroid carcinoma and weight-based dosing for hepatocellular carcinoma. Combination regimens have different dosing requirements. Dose modifications may also be necessary for certain renal or hepatic impairment.
Important Prescribing Information
Lenvatinib treatment requires monitoring because important warnings include hypertension, cardiac dysfunction, arterial thromboembolic events, and liver toxicity. Blood pressure and relevant laboratory or clinical parameters should be monitored according to the prescribing information.
Lenvatinib Prescribing Information for Pharmacy Use
Pharmacy professionals should refer to the latest approved product labeling for complete information on indications, dosage, administration, contraindications, warnings, adverse reactions, drug interactions, and dose modifications. Lenvatinib is a prescription medicine and should be supplied according to a valid prescription and applicable pharmacy regulations.